Diisobutylaluminum hydride → (E)-5-Fluoro-N-(8-(hydroxymethyl)-9-methyl-6,7-dihydro-5H-benzo[7]annulen-2-yl)picolinamide
Reaction equation
[CH3:27][CH:28]([CH2:29][AlH:30][CH2:31][CH:32]([CH3:33])[CH3:34])[CH3:35].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[NH:10][c:11]2[cH:12][cH:13][c:14]3[c:15]([cH:26]2)[C:16]([CH3:25])=[C:17]([C:21](=[O:22])[O:23][CH3:24])[CH2:18][CH2:19][CH2:20]3)[n:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[NH:10][c:11]2[cH:12][cH:13][c:14]3[c:15]([cH:26]2)[C:16]([CH3:25])=[C:17]([CH2:21][OH:22])[CH2:18][CH2:19][CH2:20]3)[n:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-6f7e7cd00c6346d5b23f914d18097af7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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