Methanol → 4-[1-[3-(Trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]benzoic acid
Reaction equation
[CH3:33][OH:34].[F:4][C:5]([c:6]1[n:7][n:8][c:9]2[n:10]1[n:11][c:12]([N:15]1[CH2:16][CH2:17][CH:18]([c:21]3[cH:22][cH:23][c:24]([C:25](=[O:26])[O:27][CH3:28])[cH:29][cH:30]3)[CH2:19][CH2:20]1)[cH:13][cH:14]2)([F:31])[F:32].[Li+:3].[OH-:2].[OH2:1].[OH2:35]>>[F:4][C:5]([c:6]1[n:7][n:8][c:9]2[n:10]1[n:11][c:12]([N:15]1[CH2:16][CH2:17][CH:18]([c:21]3[cH:22][cH:23][c:24]([C:25](=[O:26])[OH:27])[cH:29][cH:30]3)[CH2:19][CH2:20]1)[cH:13][cH:14]2)([F:31])[F:32]Participants
6
Sources & evidence
- ORD record
- ord-f6aa222de0ae40038a10fcc9d6497e68
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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