Bromide ion → 3'-Hydroxy-[1,1'-biphenyl]-3-carboxamide

HRID 689836Notes

Reaction equation

HRID 689836 reaction equation
[Br-:27].[Br:11][c:12]1[cH:13][c:14]([C:15](=[O:16])[NH2:17])[cH:18][cH:19][cH:20]1.[CH3:28][CH2:29][CH2:30][CH2:31][N+:32]([CH2:33][CH2:34][CH2:35][CH3:36])([CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH2:43][CH3:44].[CH3:45][CH2:46][OH:47].[CH3:48][CH2:49][O:50][C:51]([CH3:52])=[O:53].[K+:21].[K+:22].[O-:23][C:24]([O-:25])=[O:26].[OH:1][c:2]1[cH:3][c:4]([B:8]([OH:9])[OH:10])[cH:5][cH:6][cH:7]1.[Pd:54]([Cl:55])[Cl:56]>>[OH:1][c:2]1[cH:3][c:4](-[c:12]2[cH:13][c:14]([C:15](=[O:16])[NH2:17])[cH:18][cH:19][cH:20]2)[cH:5][cH:6][cH:7]1

Participants

10

Reactant 9

HCID 259Bromide ionHCID 702EthanolHCID 813Potassium Cation2×HCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 898073-BromobenzamideHCID 2734359(3-hydroxyphenyl)boronic Acid

Product 1

HCID 532185563'-Hydroxy-[1,1'-biphenyl]-3-carboxamide

Sources & evidence

ORD record
ord-8dde440aa7d54fd09ab8d405fe8cd326
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…