反应详情

7-(3-Chloropropoxy)-1-methyl-1H-quinolin-2-one (2.5 g) and sodium iodide (3.0 g) were added to 30 ml of acetonitrile. The mixture was stirred for 18 hours while heated under reflux. After cooled to room temperature, water was added to the reaction mixture, followed by extraction using dichloromethane. The organic layer was dried with sodium sulfate and was condensed under reduced pressure to give the title compound (2.4 g) as a pale brown powder.

1. temperaturewhile heated
2. temperatureunder reflux
3. extractionfollowed by extraction
4. dry with materialThe organic layer was dried with sodium sulfate
5. customcondensed under reduced pressure