Trifluoroacetic acid → 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-oxo-1,2-dihydro pyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea
Reaction equation
[Cl:30][c:31]1[c:32]([C:40]([F:41])([F:42])[F:43])[cH:33][c:34]([N:37]=[C:38]=[O:39])[cH:35][cH:36]1.[N-:1]=[C:2]=[O:3].[O:4]=[c:5]1[nH:6][c:7]2[c:8]([n:9][cH:10]1)[n:11][cH:12][cH:13][c:14]2[O:15][c:16]1[cH:17][cH:18][c:19]([NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[cH:20][cH:21]1.[OH:44][C:45]([C:46]([F:47])([F:48])[F:49])=[O:50]>>[O:4]=[c:5]1[nH:6][c:7]2[c:8]([n:9][cH:10]1)[n:11][cH:12][cH:13][c:14]2[O:15][c:16]1[cH:17][cH:18][c:19]([NH:22][C:23](=[O:29])[NH:37][c:34]2[cH:33][c:32]([C:40]([F:41])([F:42])[F:43])[c:31]([Cl:30])[cH:36][cH:35]2)[cH:20][cH:21]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-dd407b8f19944200935a082868ef4120
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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