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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 690238Generated: October 29, 2026

1-(3-Chloromethyl-4-methyl-pyridin-2-ylmethyl)-3-trifluoromethyl-1H-pyridin-2-one → 1-(4-Methyl-3-{2-methyl-4-[4-methyl-1-(tetrahydro-pyran-2-yl)-1H-pyrazol-3-yl]-quinolin-8-yloxymethyl}-pyridin-2-ylmethyl)-3-trifluoromethyl-1H-pyridin-2-one

https://huagongshe.com/reaction/690238

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Chloromethyl-4-methyl-pyridin-2-ylmethyl)-3-trifluoromethyl-1H-pyridin-2-oneHCID 44191035—
Reactant8-(3,5-Dichloro-pyridin-4-ylmethoxy)-4-imidazol-1-yl-2-methyl-quinolineHCID 44191138—
Reactant2-Methyl-4-[4-methyl-1-(tetrahydro-pyran-2-yl)-1H-pyrazol-3-yl]-quinolin-8-olHCID 136346374—
Product1-(4-Methyl-3-{2-methyl-4-[4-methyl-1-(tetrahydro-pyran-2-yl)-1H-pyrazol-3-yl]-quinolin-8-yloxymethyl}-pyridin-2-ylmethyl)-3-trifluoromethyl-1H-pyridin-2-oneHCID 67077182—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-d7269f3e7c074b13925a3ec84b545f1d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)