Hydrochloric Acid → 3-(5-(2,5-Difluorophenyl)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)-2-phenyl-2,3-dihydro-1,3,4-thiadiazol-2-yl)propan-1-amine

HRID 690315Notes

Reaction equation

HRID 690315 reaction equation
[CH3:37][OH:38].[CH3:39][OH:40].[ClH:36].[N:1](=[N+:2]=[N-:3])[CH2:4][CH2:5][CH2:6][C:7]1([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[S:8][C:9]([c:22]2[c:23]([F:29])[cH:24][cH:25][c:26]([F:28])[cH:27]2)=[N:10][N:11]1[c:12]1[s:13][c:14]2[c:19]([n:20]1)[CH2:18][CH2:17][N:16]([CH3:21])[CH2:15]2>>[NH2:1][CH2:4][CH2:5][CH2:6][C:7]1([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[S:8][C:9]([c:22]2[c:23]([F:29])[cH:24][cH:25][c:26]([F:28])[cH:27]2)=[N:10][N:11]1[c:12]1[s:13][c:14]2[c:19]([n:20]1)[CH2:18][CH2:17][N:16]([CH3:21])[CH2:15]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887Methanol2×HCID 866087732-(2-(3-azidopropyl)-5-(2,5-difluorophenyl)-2-phenyl-1,3,4-thiadiazol-3(2H)-yl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine

Product 1

HCID 119599503-(5-(2,5-Difluorophenyl)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)-2-phenyl-2,3-dihydro-1,3,4-thiadiazol-2-yl)propan-1-amine

Sources & evidence

ORD record
ord-7613617698be4be886d5612c85df3c36
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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