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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 690501Generated: October 29, 2026

1,2-Dichloroethane → N1-(3-Fluoro-4-(2-(1-(methoxymethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-methoxyphenyl)malonamide

https://huagongshe.com/reaction/690501

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethylformamideHCID 6228—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantN-(2-Methoxy-phenyl)-malonamic acidHCID 12664594—
Reactant3-fluoro-4-(2-(1-(methoxymethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)anilineHCID 58790224—
ProductN1-(3-Fluoro-4-(2-(1-(methoxymethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-methoxyphenyl)malonamideHCID 16041775—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-0c030864a6c647edb880403908801c66
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)