1,2-Dichloroethane → N1-(3-Fluoro-4-(2-(1-(methoxymethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-methoxyphenyl)malonamide
Reaction equation
[CH2:52]([Cl:53])[CH2:54][Cl:55].[CH3:27][O:28][c:29]1[c:30]([NH:35][C:36]([CH2:37][C:38](=[O:39])[OH:40])=[O:41])[cH:31][cH:32][cH:33][cH:34]1.[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[cH:16][c:17](-[c:19]1[n:20][cH:21][n:22]([CH2:24][O:25][CH3:26])[cH:23]1)[s:18]2.[O:56]=[CH:57][N:58]([CH3:59])[CH3:60].[OH:42][n:43]1[c:44]2[c:45]([cH:46][cH:47][cH:48][cH:49]2)[n:50][n:51]1>>[F:1][c:2]1[cH:3][c:4]([NH:5][C:38]([CH2:37][C:36]([NH:35][c:30]2[c:29]([O:28][CH3:27])[cH:34][cH:33][cH:32][cH:31]2)=[O:41])=[O:39])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[cH:16][c:17](-[c:19]1[n:20][cH:21][n:22]([CH2:24][O:25][CH3:26])[cH:23]1)[s:18]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0c030864a6c647edb880403908801c66
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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