Hydrochloric Acid → 2,2,2-Trichloroethyl 2-[4-chloro-2-(hydroxymethyl)phenyl]azetidine-1-carboxylate
Reaction equation
[Cl:17][C:18]([CH2:19][O:20][C:21](=[O:22])[Cl:23])([Cl:24])[Cl:25].[ClH:26].[ClH:3].[NH:4]1[CH:5]([c:8]2[c:9]([CH2:15][OH:16])[cH:10][c:11]([Cl:14])[cH:12][cH:13]2)[CH2:6][CH2:7]1.[Na+:2].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1.[OH-:1].[OH2:33]>>[N:4]1([C:21]([O:20][CH2:19][C:18]([Cl:17])([Cl:24])[Cl:25])=[O:22])[CH:5]([c:8]2[c:9]([CH2:15][OH:16])[cH:10][c:11]([Cl:14])[cH:12][cH:13]2)[CH2:6][CH2:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b1a8ae025463470e817c76e0235cefcc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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