Hydrochloric Acid → 4-[3-chloro-4-(1-methyl-1H-imidazole-2-ylsulfanyl)phenylamino]-7-fluoro-6-methoxyquinoline-3-carbonitrile
Reaction equation
[CH3:39][CH2:40][O:41][CH2:42][CH2:43][OH:44].[Cl:17][c:18]1[cH:19][c:20]([NH2:31])[cH:21][cH:22][c:23]1[S:24][c:25]1[n:26]([CH3:30])[cH:27][cH:28][n:29]1.[Cl:1][c:2]1[c:3]([C:15]#[N:16])[cH:4][n:5][c:6]2[cH:7][c:8]([F:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[ClH:32].[n:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[c:2]1([NH:31][c:20]2[cH:19][c:18]([Cl:17])[c:23]([S:24][c:25]3[n:26]([CH3:30])[cH:27][cH:28][n:29]3)[cH:22][cH:21]2)[c:3]([C:15]#[N:16])[cH:4][n:5][c:6]2[cH:7][c:8]([F:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d12b9cfb1771409594c21d23d34379e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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