Acetic Acid → 2-Benzyl-8-fluoro-1-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline
Reaction equation
[BH4-:29].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([c:19]2[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]2)[c:10]2[c:11]([F:18])[cH:12][cH:13][cH:14][c:15]2[CH:16]=[CH:17]1.[CH3:31][C:32](=[O:33])[OH:34].[Na+:30].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([c:19]2[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]2)[c:10]2[c:11]([F:18])[cH:12][cH:13][cH:14][c:15]2[CH2:16][CH2:17]1Participants
6
Sources & evidence
- ORD record
- ord-5f18c3bbbd5342aeaf4cdbc434fb227a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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