O-Methyltyramine → 8-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

HRID 690961Notes

Reaction equation

HRID 690961 reaction equation
[CH2:12]([CH3:13])[O:14][C:15](=[O:16])[c:17]1[c:18](=[O:40])[c:19]2[c:20]([n:21][c:22]([S:25]([CH3:26])(=[O:27])=[O:28])[n:23][cH:24]2)[n:29](-[c:31]2[cH:32][c:33]3[c:37]([cH:38][cH:39]2)[CH2:36][CH2:35][CH2:34]3)[cH:30]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][NH2:11])[cH:7][cH:8]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][NH:11][c:22]2[n:21][c:20]3[c:19]([c:18](=[O:40])[c:17]([C:15]([O:14][CH2:12][CH3:13])=[O:16])[cH:30][n:29]3-[c:31]3[cH:32][c:33]4[c:37]([cH:38][cH:39]3)[CH2:36][CH2:35][CH2:34]4)[cH:24][n:23]2)[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 4657O-MethyltyramineHCID 252229828-Indan-5-yl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

Product 1

HCID 685833418-Indan-5-yl-2-(2-(4-methoxy-phenyl)-ethylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-8e017ec9f7e44429af815761757a7d36
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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