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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 69118Generated: October 30, 2026

1,4-Dioxane hydrochloride → HCID 86694323, compound

https://huagongshe.com/reaction/69118

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ReactantHCID 86694324HCID 86694324—
SolventMethanolHCID 887—
ProductHCID 86694323HCID 86694323—

Reaction Steps

To a solution of 420 mg of tert-butyl 4-[3-(pyridin-3-yl)propyl]piperazine-1-carboxylate in 6 mL of methanol was added 2 mL of a 4 M hydrogen chloride-dioxane solution, followed by stirring at room temperature for 16 hours. The solvent was evaporated under reduced pressure to obtain 395 mg of 1-[3-(pyridin-3-yl)propyl]piperazine trihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822448B2
Source datasetuspto-grants-2014_09
ORD IDord-9210a322557b4b419cafdd1dcfd5ad8d
Source noteuspto-grants-2014_09