Dimethylformamide → Methyl 6-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1-naphthalenecarboxylate

HRID 691380Notes

Reaction equation

HRID 691380 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:46][N:47]([CH3:48])[CH:49]=[O:50].[Cl:28][CH2:29][c:30]1[c:31](-[c:38]2[c:39]([Cl:45])[cH:40][cH:41][cH:42][c:43]2[Cl:44])[n:32][o:33][c:34]1[CH:35]([CH3:36])[CH3:37].[Cs+:5].[Cs+:6].[OH:7][c:8]1[cH:9][cH:10][c:11](-[c:14]2[cH:15][c:16]3[cH:17][cH:18][cH:19][c:20]([C:24](=[O:25])[O:26][CH3:27])[c:21]3[cH:22][cH:23]2)[cH:12][cH:13]1>>[O:7]([c:8]1[cH:9][cH:10][c:11](-[c:14]2[cH:15][c:16]3[cH:17][cH:18][cH:19][c:20]([C:24](=[O:25])[O:26][CH3:27])[c:21]3[cH:22][cH:23]2)[cH:12][cH:13]1)[CH2:29][c:30]1[c:31](-[c:38]2[c:39]([Cl:45])[cH:40][cH:41][cH:42][c:43]2[Cl:44])[n:32][o:33][c:34]1[CH:35]([CH3:36])[CH3:37]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 59264867Methyl 6-(4-hydroxyphenyl)-1-naphthoateHCID 592648754-(Chloromethyl)-3-(2,6-dichlorophenyl)-5-isopropylisoxazole

Product 1

HCID 59264878Methyl 6-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1-naphthalenecarboxylate

Sources & evidence

ORD record
ord-7294bcf2eb6d4bf189f14c3b82391d47
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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