Toluene → N-methyl-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Reaction equation
[Al+3:27].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[H-:26].[H-:29].[H-:30].[H-:31].[Li+:28].[N:1]1([CH2:7][c:8]2[cH:9][c:10]3[c:15]([cH:16][cH:17]2)[CH:14]([NH:18][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:13][CH2:12][CH2:11]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([CH2:7][c:8]2[cH:9][c:10]3[c:15]([cH:16][cH:17]2)[CH:14]([NH:18][CH3:19])[CH2:13][CH2:12][CH2:11]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
6
Sources & evidence
- ORD record
- ord-c19cb2301a82422b9bbd8e1f24b9be83
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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