Acetone → N-[2-(4-(2-Hydroxyethoxy)-phenyl)-1-methylethyl]-2-(6-chloro-pyridin-2-yl)-morpholine

HRID 691679Notes

Reaction equation

HRID 691679 reaction equation
[BH3:42].[CH3:28][C:29](=[O:30])[CH3:31].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1.[OH:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH2:11][CH:12]([CH3:13])[N:14]2[CH2:15][CH:16]([c:21]3[n:22][c:23]([Cl:27])[cH:24][cH:25][cH:26]3)[O:17][CH2:18][C:19]2=[O:20])[cH:9][cH:10]1>>[OH:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH2:11][CH:12]([CH3:13])[N:14]2[CH2:15][CH:16]([c:21]3[n:22][c:23]([Cl:27])[cH:24][cH:25][cH:26]3)[O:17][CH2:18][CH2:19]2)[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 180AcetoneHCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 14578858N-[2-(4-(2-Hydroxyethoxy)-phenyl)-1-methylethyl]-2-(6-chloro-pyridin-2-yl)-morpholin-5-one

Product 1

HCID 14578859N-[2-(4-(2-Hydroxyethoxy)-phenyl)-1-methylethyl]-2-(6-chloro-pyridin-2-yl)-morpholine

Sources & evidence

ORD record
ord-df1fa431e93b4235bc7b786d4dcd53db
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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