Dichloromethane → 1-(2-(4-(2-Bromo-6-methoxy-3,4-dihydronaphthalen-1-yloxy)phenoxy)ethyl)piperidine

HRID 691760Notes

Reaction equation

HRID 691760 reaction equation
[Br:39][N:40]1[C:41](=[O:42])[CH2:43][CH2:44][C:45]1=[O:46].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[C:9]([O:13][c:14]1[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]3[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]3)[cH:18][cH:19]1)=[C:8]([C:29]([OH:30])=[O:31])[CH2:7][CH2:6]2.[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cl:47][CH2:48][Cl:49]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[C:9]([O:13][c:14]1[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]3[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]3)[cH:18][cH:19]1)=[C:8]([Br:39])[CH2:7][CH2:6]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 67184N-bromobutanimideHCID 583385566-Methoxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)-3,4-dihydronaphthalene-2-carboxylic acid

Product 1

HCID 583385381-(2-(4-(2-Bromo-6-methoxy-3,4-dihydronaphthalen-1-yloxy)phenoxy)ethyl)piperidine

Sources & evidence

ORD record
ord-309d2c8d3e7c402a8a11e31ecca939ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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