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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 692397Generated: October 30, 2026

Water → 1'-Benzyl-6-chloro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one

https://huagongshe.com/reaction/692397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDiethyl EtherHCID 3283—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
Reactant1-Benzyl-4-piperidoneHCID 19220—
Reactant2-Bromo-4-chlorobenzoic acidHCID 33126—
ReactantButyllithiumHCID 178418339—
Product1'-Benzyl-6-chloro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-oneHCID 12213047—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-14a29471ac124b7087151805951c20e9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)