Water → 1'-Benzyl-6-chloro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Reaction equation
[Br:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([Cl:11])[cH:10]1.[CH2:12]([c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)[N:19]1[CH2:20][CH2:21][C:22](=[O:25])[CH2:23][CH2:24]1.[CH2:43]([Li:44])[CH2:45][CH2:46][CH3:47].[CH3:27][CH2:28][O:29][CH2:30][CH3:31].[CH3:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[OH2:26]>>[c:2]12[c:3]([cH:7][cH:8][c:9]([Cl:11])[cH:10]1)[C:4](=[O:5])[O:6][C:22]21[CH2:21][CH2:20][N:19]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:24][CH2:23]1Participants
8
Sources & evidence
- ORD record
- ord-14a29471ac124b7087151805951c20e9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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