Dichloromethane → 6-Fluoro-4-iodopyridin-3-amine

HRID 692937Notes

Reaction equation

HRID 692937 reaction equation
[Cl:24][CH2:25][Cl:26].[F:1][c:2]1[cH:3][c:4]([I:16])[c:5]([NH:8][C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[cH:6][n:7]1.[OH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23]>>[F:1][c:2]1[cH:3][c:4]([I:16])[c:5]([NH2:8])[cH:6][n:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 66738095(6-Fluoro-4-iodo-pyridin-3-yl)-carbamic acid tert-butyl ester

Product 1

HCID 582666416-Fluoro-4-iodopyridin-3-amine

Sources & evidence

ORD record
ord-7800b268e9284d9d9bdba17c474503a4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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