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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 693011Generated: October 31, 2026

Dichloromethane → 1-Oxa-2-aza-spiro[4.5]dec-2-ene-3-carboxylic acid [4-amino-5-(3-hydroxy-3-methyl-butyl)-2'-trifluoromethyl-biphenyl-3-yl]-amide

https://huagongshe.com/reaction/693011

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-Oxa-2-azaspiro[4.5]dec-2-ene-3-carboxylic acidHCID 50994114—
Reactant4-(4,5-Diamino-2'-trifluoromethyl-biphenyl-3-yl)-2-methyl-butan-2-olHCID 59280103—
Product1-Oxa-2-aza-spiro[4.5]dec-2-ene-3-carboxylic acid [4-amino-5-(3-hydroxy-3-methyl-butyl)-2'-trifluoromethyl-biphenyl-3-yl]-amideHCID 59280092—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-e713eb4234c045488904e4c382c52be1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)