Dimethyl Sulfoxide → Tert-butyl 2-[6-[(3-methylbenzoyl)amino]pyrazin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

HRID 693377Notes

Reaction equation

HRID 693377 reaction equation
[CH2:18]1[N:19]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:20][CH:21]2[CH:22]1[CH2:23][NH:24][CH2:25]2.[CH3:42][S:43]([CH3:44])=[O:45].[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([NH:8][C:9]([c:10]2[cH:11][c:12]([CH3:16])[cH:13][cH:14][cH:15]2)=[O:17])[n:7]1>>[c:2]1([N:24]2[CH2:23][CH:22]3[CH2:18][N:19]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:20][CH:21]3[CH2:25]2)[cH:3][n:4][cH:5][c:6]([NH:8][C:9]([c:10]2[cH:11][c:12]([CH3:16])[cH:13][cH:14][cH:15]2)=[O:17])[n:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 81531DiisopropylethylamineHCID 4142526Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylateHCID 86635811N-(6-chloropyrazin-2-yl)-3-methylbenzamide

Product 1

HCID 67265308Tert-butyl 2-[6-[(3-methylbenzoyl)amino]pyrazin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

Sources & evidence

ORD record
ord-d2d5c28482af4a9598831c6ca5e418b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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