Methanol → {1-[6-(3,4-Difluoro-phenoxy)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-2,2-dimethyl-propyl}-carbamic acid benzyl ester
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]2[CH:10]([CH:11]([O:13][c:14]3[cH:15][c:16]([F:21])[c:17]([F:20])[cH:18][cH:19]3)[CH2:12]1)[N:22]([C:25]([CH:26]([C:27]([CH3:28])([CH3:29])[CH3:30])[NH:31][C:32](=[O:33])[O:34][CH2:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1)=[O:42])[CH2:23][CH2:24]2)([CH3:5])([CH3:6])[CH3:7].[CH3:53][OH:54].[Cl:50][CH2:51][Cl:52].[Cl:55][CH2:56][Cl:57].[F:43][C:44]([F:45])([F:46])[C:47]([OH:48])=[O:49]>>[NH:8]1[CH:9]2[CH:10]([CH:11]([O:13][c:14]3[cH:15][c:16]([F:21])[c:17]([F:20])[cH:18][cH:19]3)[CH2:12]1)[N:22]([C:25]([CH:26]([C:27]([CH3:28])([CH3:29])[CH3:30])[NH:31][C:32](=[O:33])[O:34][CH2:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1)=[O:42])[CH2:23][CH2:24]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-13e74a6957964497b2a12afefce9019f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…