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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 693679Generated: October 26, 2026

Tetrahydrofuran → N-[2-chloro-4-[2-(dimethylamino)-2-oxoethyl]sulfanylphenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide

https://huagongshe.com/reaction/693679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant2-chloro-N,N-dimethylacetamideHCID 75886—
ReactantN-[2-chloro-4-tri(propan-2-yl)silylsulfanylphenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamideHCID 22287265—
ProductN-[2-chloro-4-[2-(dimethylamino)-2-oxoethyl]sulfanylphenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamideHCID 22287418—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-5beedb817d4e4f7e98966ebf4b250d65
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)