Tetrahydrofuran → N-[2-chloro-4-[2-(dimethylamino)-2-oxoethyl]sulfanylphenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Reaction equation
[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[Cl:19][c:20]1[c:21]([NH:37][C:38]([C:39]([C:40]([F:41])([F:42])[F:43])([CH3:44])[OH:45])=[O:46])[cH:22][cH:23][c:24]([S:26][Si:27]([CH:28]([CH3:29])[CH3:30])([CH:31]([CH3:32])[CH3:33])[CH:34]([CH3:35])[CH3:36])[cH:25]1.[Cl:47][CH2:48][C:49](=[O:50])[N:51]([CH3:52])[CH3:53].[F-:1]>>[Cl:19][c:20]1[c:21]([NH:37][C:38]([C:39]([C:40]([F:41])([F:42])[F:43])([CH3:44])[OH:45])=[O:46])[cH:22][cH:23][c:24]([S:26][CH2:48][C:49](=[O:50])[N:51]([CH3:52])[CH3:53])[cH:25]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5beedb817d4e4f7e98966ebf4b250d65
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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