Acetic Acid → 1-[2-(3-Amino-pyrrolidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea

HRID 694079Notes

Reaction equation

HRID 694079 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][N:10]([CH2:13][CH2:14][NH:15][C:16](=[O:17])[NH:18][c:19]2[cH:20][c:21]([CH3:29])[n:22][c:23]3[cH:24][cH:25][cH:26][cH:27][c:28]23)[CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:30].[C:32]([OH:33])(=[O:34])[CH3:35].[ClH:31]>>[NH2:7][CH:8]1[CH2:9][N:10]([CH2:13][CH2:14][NH:15][C:16](=[O:17])[NH:18][c:19]2[cH:20][c:21]([CH3:29])[n:22][c:23]3[cH:24][cH:25][cH:26][cH:27][c:28]23)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 59715918(1-{2-[3-(2-Methyl-quinolin-4-yl)-ureido]-ethyl}-pyrrolidin-3-yl)-carbamic acid tert-butyl ester

Product 1

HCID 597159171-[2-(3-Amino-pyrrolidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea

Sources & evidence

ORD record
ord-79943c6c6ee74fb39c188875fa94218c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…