3-(N-tert-Butoxycarbonyl-N-methylamino)pyrrolidine → Hydrochloric Acid

HRID 694256Notes

Reaction equation

HRID 694256 reaction equation
[Br:30][c:31]1[c:32]2[c:33]([S:34]([Cl:35])(=[O:36])=[O:37])[cH:38][cH:39][cH:40][c:41]2[cH:42][n:43][cH:44]1.[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[N:23]([CH3:24])[CH:25]1[CH2:26][NH:27][CH2:28][CH2:29]1.[C:45]([O:46][C:47]([N:48]([CH:49]1[CH2:50][CH2:51][NH:52][CH2:53]1)[CH3:54])=[O:55])([CH3:56])([CH3:57])[CH3:58].[F:1][c:2]1[cH:3][n:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([S:12](=[O:13])(=[O:14])[Cl:15])[c:11]12>>[ClH:15].[F:1][c:2]1[cH:3][n:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([S:12](=[O:13])(=[O:14])[N:27]3[CH2:26][CH:25]([N:23]([C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH3:24])[CH2:29][CH2:28]3)[c:11]12

Participants

5

Reactant 3

HCID 27614043-(N-tert-Butoxycarbonyl-N-methylamino)pyrrolidine2×HCID 118565474-Fluoroisoquinoline-5-sulfonylchlorideHCID 145800584-Bromo-5-isoquinolinesulfonyl chloride

Product 2

HCID 313Hydrochloric AcidHCID 672426833-[n-(Tert-butoxycarbonyl)-n-methylamino]-1-(4-fluoro-5-isoquinolinesulfonyl)pyrrolidine

Sources & evidence

ORD record
ord-1048ff48a4be40e8b2f6feeb9b0c6925
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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