Hydrogen Bromide → HCID 68992779, compound

HRID 69433Notes

Reaction equation

HRID 69433 reaction equation
[N:1]1([C@@H:6]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH2:26][CH2:25][C:24]5[C:19](=[CH:20][CH:21]=[C:22]([O:27]C)[CH:23]=5)[C:18]4=[O:29])=[CH:13][C:12]=3[F:30])[CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.Br>>[N:1]1([C@@H:6]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH2:26][CH2:25][C:24]5[C:19](=[CH:20][CH:21]=[C:22]([OH:27])[CH:23]=5)[C:18]4=[O:29])=[CH:13][C:12]=3[F:30])[CH2:7]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 579169542-((R)-4-[1,3']bipyrrolidinyl-1'-yl-3-fluorophenyl)-6-methoxy-3,4-dihydro-2H-isoquinolin-1-one

Product 1

HCID 68992779HCID 68992779, compound

Procedure

According to Method L, 2-((R)-4-[1,3′]bipyrrolidinyl-1′-yl-3-fluorophenyl)-6-methoxy-3,4-dihydro-2H-isoquinolin-1-one was reacted with hydrogen bromide. In this way the product was obtained with molecular weight 395.48 (C23H26FN3O2); MS (ESI): 396 (M+H+).

Workup

  1. customIn this way the product was obtained with molecular weight 395.48 (C23H26FN3O2)

Sources & evidence

ORD record
ord-39c488eca6e3452face1cf9f6610f4e8
Source dataset
uspto-grants-2014_09
Patent number
US08822495B2

Reaction notes

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