Trifluoroacetic acid → 4-Cyclopropylethynyl-6-hydroxy-4-trifluoromethyl-1,4-dihydro-benzo [d][1,3]oxazin-2-one

HRID 694418Notes

Reaction equation

HRID 694418 reaction equation
[CH:1]1([C:4]#[C:5][C:6]2([C:24]([F:25])([F:26])[F:27])[c:7]3[c:8]([cH:13][cH:14][c:15]([O:17][CH2:18][O:19][CH2:20][CH2:21][O:22][CH3:23])[cH:16]3)[NH:9][C:10](=[O:12])[O:11]2)[CH2:2][CH2:3]1.[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[CH:1]1([C:4]#[C:5][C:6]2([C:24]([F:25])([F:26])[F:27])[c:7]3[c:8]([cH:13][cH:14][c:15]([OH:17])[cH:16]3)[NH:9][C:10](=[O:12])[O:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 688005564-Cyclopropylethynyl-6-(2-methoxy-ethoxymethoxy)-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one

Product 1

HCID 114264734-Cyclopropylethynyl-6-hydroxy-4-trifluoromethyl-1,4-dihydro-benzo [d][1,3]oxazin-2-one

Sources & evidence

ORD record
ord-f140559095d24c46886a3463f4548163
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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