Dimethylformamide → tert-Butyl 2-(7-(4-Cyclopentyl-3-(trifluoromethyl)benzyloxy)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate

HRID 694486Notes

Reaction equation

HRID 694486 reaction equation
[C:39](=[O:40])([O-:41])[O-:42].[Cl:22][CH2:23][c:24]1[cH:25][c:26]([C:35]([F:36])([F:37])[F:38])[c:27]([CH:30]2[CH2:31][CH2:32][CH2:33][CH2:34]2)[cH:28][cH:29]1.[Cs+:43].[Cs+:44].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49].[OH:1][c:2]1[cH:3][c:4]2[cH:5][c:6]3[n:7]([c:8]2[cH:9][cH:10]1)[CH2:11][CH2:12][CH:13]3[CH2:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21]>>[O:1]([c:2]1[cH:3][c:4]2[cH:5][c:6]3[n:7]([c:8]2[cH:9][cH:10]1)[CH2:11][CH2:12][CH:13]3[CH2:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:23][c:24]1[cH:25][c:26]([C:35]([F:36])([F:37])[F:38])[c:27]([CH:30]2[CH2:31][CH2:32][CH2:33][CH2:34]2)[cH:28][cH:29]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 534026024-(Chloromethyl)-1-cyclopentyl-2-(trifluoromethyl)benzeneHCID 67249455tert-butyl 2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate

Product 1

HCID 67248866tert-Butyl 2-(7-(4-Cyclopentyl-3-(trifluoromethyl)benzyloxy)-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate

Sources & evidence

ORD record
ord-e5a042ac946a45ddb65b52d31b9e829e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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