HRID69450

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID20417

4-Morpholinecarboxaldehyde

C5H9NO2

结构：COc1cc(NC(=O)c2ccc(OCc3ccccc3)cc2C)ccc1N1CC[C@@H](N2CCCC2)C1

HCID68988853

未命名化合物

PRODUCTS

生成物

结构：COc1cc(-n2ccc3cc(OCc4ccccc4)ccc3c2=O)ccc1N1CC[C@@H](N2CCCC2)C1

HCID68990095

未命名化合物

PROCEDURE

实验过程

According to Method Q, 4-benzyloxy-N—((R)-4-[1,3′]bipyrrolidinyl-1′-yl-3-methoxy-phenyl)-2-methyl-benzamide was reacted with N-formylmorpholine. In this way the product was obtained with molecular weight 495.63 (C31H33N3O3); MS (ESI): 496 (M+H+).

WORKUP

后处理

customIn this way the product was obtained with molecular weight 495.63 (C31H33N3O3)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c03e5af6b18b47b098c8f2fbfa3a8f17
来源数据集: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08822495B2
来源说明: uspto-grants-2014_09

反应 SMILES

[CH2:1]([O:8][C:9]1[CH:35]=[CH:34][C:12]([C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([N:22]3[CH2:26][CH2:25][C@@H:24]([N:27]4[CH2:31][CH2:30][CH2:29][CH2:28]4)[CH2:23]3)=[C:18]([O:32][CH3:33])[CH:17]=2)=[O:14])=[C:11]([CH3:36])[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:37](N1CCOCC1)=O>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]2[C:12](=[CH:34][CH:35]=1)[C:13](=[O:14])[N:15]([C:16]1[CH:21]=[CH:20][C:19]([N:22]3[CH2:26][CH2:25][C@@H:24]([N:27]4[CH2:31][CH2:30][CH2:29][CH2:28]4)[CH2:23]3)=[C:18]([O:32][CH3:33])[CH:17]=1)[CH:37]=[CH:36]2)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1