Toluene → 5-(2,4-difluoro-phenylethynyl)-3-(2,2-dimethyl-propyl)-3H-imidazo[4,5-b]pyridin-2-ylamine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[n:8]([CH2:12][C:13]([CH3:14])([CH3:15])[CH3:16])[c:9]([NH2:11])[n:10]2.[C:24](#[CH:25])[c:26]1[c:27]([F:33])[cH:28][c:29]([F:32])[cH:30][cH:31]1.[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[c:2]1([C:25]#[C:24][c:26]2[c:27]([F:33])[cH:28][c:29]([F:32])[cH:30][cH:31]2)[cH:3][cH:4][c:5]2[c:6]([n:7]1)[n:8]([CH2:12][C:13]([CH3:14])([CH3:15])[CH3:16])[c:9]([NH2:11])[n:10]2Participants
5
Sources & evidence
- ORD record
- ord-f0ebab3762414f1f9e4b8ed82669e15b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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