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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 69480Generated: October 29, 2026

Azetidine → HCID 57916886, compound

https://huagongshe.com/reaction/69480

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzetidineHCID 10422—
Reactant2-[3-Fluoro-4-(3-oxo-pyrrolidin-1-yl)-phenyl]-6-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-2H-isoquinolin-1-oneHCID 68992023—
ProductHCID 57916886HCID 57916886—

Reaction Steps

2-[3-Fluoro-4-(3-oxo-pyrrolidin-1-yl)-phenyl]-6-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-2H-isoquinolin-1-one was reacted with azetidine according to Method J1. In this way the product was obtained with molecular weight 463.23 (C27H30FN3O3); MS (ESI): 464 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822495B2
Source datasetuspto-grants-2014_09
ORD IDord-52adfe9780ca4fe0aef807fab6d3b882
Source noteuspto-grants-2014_09