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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 69481Generated: October 26, 2026

(R)-(tetrahydrofuran-2-yl)methyl methanesulfonate → HCID 68991422, compound

https://huagongshe.com/reaction/69481

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-(tetrahydrofuran-2-yl)methyl methanesulfonateHCID 18649742—
ReactantHCID 68990655HCID 68990655—
ProductHCID 68991422HCID 68991422—

Reaction Steps

2-[4-(1,4-Dioxa-7-aza-spiro[4.4]non-7-yl)-3-fluorophenyl]-6-hydroxy-2H-isoquinolin-1-one was reacted with (R)-methanesulfonic acid tetrahydrofuran-2-ylmethyl ester according to Method K1. In this way the product was obtained with molecular weight 466.19 (C26H27FN2O5); MS (ESI): 467 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822495B2
Source datasetuspto-grants-2014_09
ORD IDord-08fa862a8dba46e7a1be861416f9d370
Source noteuspto-grants-2014_09