2-Amino-5-(trifluoromethyl)pyridine → (7-Bromo-quinazolin-4-yl)-(5-trifluoromethyl-pyridin-2-yl)-amine

HRID 694812Notes

Reaction equation

HRID 694812 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([Cl:12])[n:7][cH:8][n:9][c:10]2[cH:11]1.[NH2:13][c:14]1[n:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([NH:13][c:14]3[n:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]3)[n:7][cH:8][n:9][c:10]2[cH:11]1

Participants

3

Reactant 2

HCID 7358622-Amino-5-(trifluoromethyl)pyridineHCID 167808557-Bromo-4-chloroquinazoline

Product 1

HCID 11485491(7-Bromo-quinazolin-4-yl)-(5-trifluoromethyl-pyridin-2-yl)-amine

Sources & evidence

ORD record
ord-c5ce7556e39f423a906e13271612e2d1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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