HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-[(R)-1-(Tetrahydrofuran-2-yl)methoxy]isochromen-1-one → 2-((R)-3-Acetyl-4-[1,3']bipyrrolidinyl-1'-yl-phenyl)-6-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-2H-isoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-[(R)-1-(Tetrahydrofuran-2-yl)methoxy]isochromen-1-one | HCID 66878936 | — |
| Reactant | 1-((R)-5-amino-2-[1,3']bipyrrolidinyl-1'-yl-phenyl)-ethanone | HCID 68992420 | — |
| Product | 2-((R)-3-Acetyl-4-[1,3']bipyrrolidinyl-1'-yl-phenyl)-6-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-2H-isoquinolin-1-one | HCID 57916845 | — |
Reaction Steps
6-[(R)-1-(Tetrahydrofuran-2-yl)methoxy]-isochromen-1-one and 1-((R)-5-amino-2-[1,3′]bipyrrolidinyl-1′-yl-phenyl)-ethanone were reacted according to Method AJ. In this way the product was obtained with molecular weight 501.63 (C30H35N3O4); MS (ESI): 502 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822495B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-d5186c216b384281ba8587983efdd721 |
| Source note | uspto-grants-2014_09 |