Carbonate Ion → 2-Chloro-3-ethyl-4-[3-(2-hydroxypropan-2-yl)-2-methylpyrrolidin-1-yl]benzonitrile
Reaction equation
[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([F:12])[c:9]1[CH2:10][CH3:11].[Li+:23].[Li+:24].[O-:25][C:26](=[O:27])[O-:28].[OH:13][C:14]([CH3:15])([CH3:16])[CH:17]1[CH:18]([CH3:22])[NH:19][CH2:20][CH2:21]1>>[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([N:19]2[CH:18]([CH3:22])[CH:17]([C:14]([OH:13])([CH3:15])[CH3:16])[CH2:21][CH2:20]2)[c:9]1[CH2:10][CH3:11]Participants
5
Sources & evidence
- ORD record
- ord-5fa9c4fcfc1949c8b73b8a8cc7bd68d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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