Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-hydroxy-5-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-indan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | HCID 68991904 | HCID 68991904 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-hydroxy-5-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-indan-1-one | HCID 68988098 | — |
반응 단계
A mixture of acetic acid 1-oxo-5-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-indan-2-yl ester (1.02 g) and potassium carbonate (264 mg) in methanol (1 mL) was stirred at room temperature for 1 h. After adding water it was extracted with dichloromethane, dried over magnesium sulfate and concentrated. In this way the product was obtained with molecular weight 248.28 (C14H16O4); MS (ESI): 249 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822495B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-eb16fef3c4844969a757d0d907d475fe |
| 출처 메모 | uspto-grants-2014_09 |