Hydrochloric Acid → 1-[3-[4-[3,5-bis(trifluoromethyl)benzoyl]-3-(1H-indol-3-ylmethyl)piperazin-1-yl]propyl]-4-phenylpiperidine-4-carbonitrile
Reaction equation
[C:42](#[N:43])[C:44]1([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[CH2:45][CH2:46][NH:47][CH2:48][CH2:49]1.[CH3:62][OH:63].[ClH:41].[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:22][c:23]3[cH:24][nH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]34)[CH2:10][N:11]([CH2:14][CH2:15][CH2:16][O:17][S:18]([CH3:19])(=[O:20])=[O:21])[CH2:12][CH2:13]2)[cH:32][c:33]([C:35]([F:36])([F:37])[F:38])[cH:34]1)([F:39])[F:40].[Na+:56].[Na+:57].[O-:58][C:59](=[O:60])[O-:61]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:22][c:23]3[cH:24][nH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]34)[CH2:10][N:11]([CH2:14][CH2:15][CH2:16][N:47]3[CH2:46][CH2:45][C:44]([C:42]#[N:43])([c:50]4[cH:51][cH:52][cH:53][cH:54][cH:55]4)[CH2:49][CH2:48]3)[CH2:12][CH2:13]2)[cH:32][c:33]([C:35]([F:36])([F:37])[F:38])[cH:34]1)([F:39])[F:40]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fc5cba954f094b689770129b4b36f1f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…