Water → Ganciclovir

HRID 695332Notes

Reaction equation

HRID 695332 reaction equation
[C:40]([O:41][CH2:42][CH:43]([O:44][C:45](=[O:46])[CH3:47])[CH:48]([O:49][C:50](=[O:51])[CH3:52])[CH2:53][O:54][CH2:55][CH:56]([O:57][C:58](=[O:59])[CH3:60])[CH:61]([O:62][C:63](=[O:64])[CH3:65])[CH2:66][O:67][C:68](=[O:69])[CH3:70])(=[O:71])[CH3:72].[CH3:1][C:2]([O:3][C:4](=[O:5])[CH3:6])=[O:7].[NH2:20][c:21]1[n:22][c:23]2[n:24]([CH:31]3[O:32][CH:33]([CH2:34][OH:35])[CH:36]([OH:37])[CH:38]3[OH:39])[cH:25][n:26][c:27]2[c:28](=[O:29])[nH:30]1.[OH2:8].[c:9]1([CH3:10])[cH:11][cH:12][c:13]([S:14]([OH:15])(=[O:16])=[O:17])[cH:18][cH:19]1>>[NH2:20][c:21]1[n:22][c:23]2[n:24]([CH2:31][O:32][CH:33]([CH2:34][OH:35])[CH2:36][OH:37])[cH:25][n:26][c:27]2[c:28](=[O:29])[nH:30]1

Participants

6

Reactant 5

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 7918Acetic AnhydrideHCID 57278494[2,3-Diacetyloxy-4-(2,3,4-triacetyloxybutoxy)butyl] acetateHCID 1354020342-amino-9-(3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-3H-purin-6-one

Product 1

HCID 135398740Ganciclovir

Sources & evidence

ORD record
ord-07b55f0623064a8ea2fea35205d49772
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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