Dichloromethane → Morpholin-3-ylmethyl 4-phenylpiperazine-1-carboxylate

HRID 695365Notes

Reaction equation

HRID 695365 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:14][O:15][C:16](=[O:17])[N:18]2[CH2:19][CH2:20][N:21]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[CH2:22][CH2:23]2)[CH2:10][O:11][CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:37][CH2:38][Cl:39].[F:30][C:31]([F:32])([F:33])[C:34]([OH:35])=[O:36]>>[NH:8]1[CH:9]([CH2:14][O:15][C:16](=[O:17])[N:18]2[CH2:19][CH2:20][N:21]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[CH2:22][CH2:23]2)[CH2:10][O:11][CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 669345083-(4-Phenyl-piperazine-1-carbonyloxymethyl)-morpholine-4-carboxylic acid tert-butyl ester

Product 1

HCID 42634520Morpholin-3-ylmethyl 4-phenylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-70616290a7764707ac3be7f4e99a4a12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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