Tetrahydrofuran → methyl 5-amino-4-[7-(1-benzothiophen-5-ylmethoxy)-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate
Reaction equation
[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[NH2:15][C:16]([CH:17]([CH2:18][CH2:19][C:20](=[O:21])[O:22][CH3:23])[N:24]1[C:25](=[O:34])[c:26]2[cH:27][cH:28][cH:29][c:30]([OH:33])[c:31]2[CH2:32]1)=[O:35].[O:1]=[C:2]([O:3][CH:4]([CH3:5])[CH3:6])[N:7]=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14].[s:36]1[cH:37][cH:38][c:39]2[c:40]1[cH:41][cH:42][c:43]([CH2:45][OH:46])[cH:44]2>>[NH2:15][C:16]([CH:17]([CH2:18][CH2:19][C:20](=[O:21])[O:22][CH3:23])[N:24]1[C:25](=[O:34])[c:26]2[cH:27][cH:28][cH:29][c:30]([O:33][CH2:45][c:43]3[cH:42][cH:41][c:40]4[s:36][cH:37][cH:38][c:39]4[cH:44]3)[c:31]2[CH2:32]1)=[O:35]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-95944ac4fd8d47f9a3635688eb05efea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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