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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 695646Generated: October 25, 2026

2-(Bromomethyl)tetrahydro-2H-pyran → 5-fluoro-6-methoxy-1'-(oxolan-2-ylmethyl)spiro[2H-1-benzofuran-3,3'-indole]-2'-one

https://huagongshe.com/reaction/695646

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)tetrahydro-2H-pyranHCID 141917—
Reactant(Tetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonateHCID 4522871—
Reactant5-fluoro-6-methoxyspiro[1-benzofuran-3,3'-indol]-2'(1'H)-oneHCID 46194048—
Product5-fluoro-6-methoxy-1'-(oxolan-2-ylmethyl)spiro[2H-1-benzofuran-3,3'-indole]-2'-oneHCID 72268582—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-a043aad6ba934e8daa4acde5cda027ac
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)