Sodium ion → tert-Butyl 4-(4-chlorophenyl)-4-cyanopiperidine-1-carboxylate
Reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]([CH2:21][CH2:22][Cl:26])[CH2:24][CH2:25][Cl:23].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][C:7]#[N:8])[cH:9][cH:10]1.[H-:11].[N:27]1([C:28]#[N:29])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1.[Na+:12].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6]2([C:7]#[N:8])[CH2:22][CH2:21][N:20]([C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[CH2:24][CH2:25]2)[cH:9][cH:10]1Participants
7
Sources & evidence
- ORD record
- ord-bf79de07b1c04303829762d4e7681f9c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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