Isopropanol → 6-[4-[2-[3-(5-chloro-2-cyanophenoxy)-2-hydroxypropylamino]-2-methylpropylamino]-phenyl]-4,5-dihydro-3(2H)-pyridazinone
Reaction equation
[CH:34]([OH:35])([CH3:36])[CH3:37].[Cl:20][c:21]1[cH:22][cH:23][c:24]([C:32]#[N:33])[c:25]([O:26][CH2:27][CH:28]2[CH2:29][O:30]2)[cH:31]1.[NH2:1][C:2]([CH2:3][NH:4][c:5]1[cH:6][cH:7][c:8]([C:11]2=[N:16][NH:15][C:14](=[O:17])[CH2:13][CH2:12]2)[cH:9][cH:10]1)([CH3:18])[CH3:19]>>[NH:1]([C:2]([CH2:3][NH:4][c:5]1[cH:6][cH:7][c:8]([C:11]2=[N:16][NH:15][C:14](=[O:17])[CH2:13][CH2:12]2)[cH:9][cH:10]1)([CH3:18])[CH3:19])[CH2:29][CH:28]([CH2:27][O:26][c:25]1[c:24]([C:32]#[N:33])[cH:23][cH:22][c:21]([Cl:20])[cH:31]1)[OH:30]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0e940f1fb1e0482f88b810bb1711462e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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