Tetrahydrofuran → 5-Bromo-2-cyclopropylpyridine

HRID 695834Notes

Reaction equation

HRID 695834 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1.[CH2:9]1[CH2:10][CH2:11][CH2:12][O:13]1.[cH:14]1[cH:15][cH:16][c:17]([P:18]([Pd:19]([P:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[cH:89][cH:90]1>>[c:2]1([CH:10]2[CH2:11][CH2:12]2)[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 693532,5-DibromopyridineHCID 178420554HCID 178420554, compound

Product 1

HCID 223177225-Bromo-2-cyclopropylpyridine

Sources & evidence

ORD record
ord-b07bf6ed531f48fdb11547707a3a7cdc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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