Acetate → 4-Hydroxy-4-(4-pyrimidin-2-ylphenyl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:33][c:34]1[n:35][cH:36][cH:37][cH:38][n:39]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([c:15]2[cH:16][cH:17][c:18]([Br:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[C:27](=[O:28])([O-:29])[O-:30].[CH3:23][C:24](=[O:25])[O-:26].[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[CH3:47][S:48]([CH3:49])=[O:50].[K+:22].[K+:31].[K+:32].[OH2:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([c:15]2[cH:16][cH:17][c:18](-[c:34]3[n:35][cH:36][cH:37][cH:38][n:39]3)[cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-cbfed189f4a84e2199afae5a66947b10
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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