Diisopropylamine → (5-Bromo-2-fluoro-pyridin-3-yl)-(2-methoxy-phenyl)-methanone
Reaction equation
[Br:19][c:20]1[cH:21][cH:22][c:23]([F:26])[n:24][cH:25]1.[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:27][O:28][c:29]1[c:30]([C:31](=[O:32])[N:33]([O:34][CH3:35])[CH3:36])[cH:37][cH:38][cH:39][cH:40]1.[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7]>>[Br:19][c:20]1[cH:21][c:22]([C:31]([c:30]2[c:29]([O:28][CH3:27])[cH:40][cH:39][cH:38][cH:37]2)=[O:32])[c:23]([F:26])[n:24][cH:25]1Participants
7
Sources & evidence
- ORD record
- ord-c1db2a8f91254bff82868f842999aa24
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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