Dichloromethane → 5-(Chloromethyl)-2-(methylthio)pyrimidine

HRID 696735Notes

Reaction equation

[CH3:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17].[CH3:18][S:19]([Cl:20])(=[O:21])=[O:22].[CH3:1][S:2][c:3]1[n:4][cH:5][c:6]([CH2:9][OH:10])[cH:7][n:8]1.[Cl:23][CH2:24][Cl:25]>>[CH3:1][S:2][c:3]1[n:4][cH:5][c:6]([CH2:9][Cl:20])[cH:7][n:8]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 8471Triethylamine

HCID 31297Methanesulfonyl chloride

HCID 22050485(2-(Methylsulfanyl)pyrimidin-5-yl)methanol

Product 1

HCID 220509705-(Chloromethyl)-2-(methylthio)pyrimidine

Sources & evidence

ORD record: ord-105bab7b646c435a8be1b75d5e1a72d0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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